Cytohesin 1 interacting protein
WebThe CYTH1 is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. CYTH1 protein is … WebFour cytohesin family members are known – cytohesin-1, -2 ... (NOEs), which detect protein–protein interactions through space, for the αIIb–β3 mixture were lost in the …
Cytohesin 1 interacting protein
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WebJun 4, 2009 · Our laboratory has identified the guanine nucleotide exchange factor (GEF) for ADP-ribosylation factor (ARF) GTPases, cytohesin-1, as an LFA-1 interacting protein. Cytohesin-1 binds specifically to the cytoplasmic portion of the integrin beta-2 subunit CD18. 19 In Jurkat T cells, overexpression of cytohesin-1 results in up-regulation of LFA … WebWhen expressed in the cytoplasm of T cells, aptamers selected against either the intracellular domain of the human β2 integrin LFA-1 or the Sec7 sub-domain of its interacting partner cytohesin 1 (cyh1) specifically inhibited LFA-1-mediated T-cell adhesion to ICAM-1.
Webcytohesin 1 interacting protein Synonyms A130053M09Rik, Cbp, Cybr, Pscdbp Feature Type protein coding gene IDs MGI:2183535 NCBI Gene: 227929 Alliance gene page … WebJun 6, 2000 · The cytohesin-1-interacting region in CD18 comprises the membrane-proximal segment of the β-2 cytoplasmic domain, ... It seems plausible, therefore, that …
WebIn summary, we identified IPCEF1 as a novel cytohesin-interacting protein by yeast two-hybrid screening. IPCEF1 shows no noticeable … WebCytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor [13]. Investigations into the interaction between the Sec7 domain and the beta2 integrin cytoplasmic domain suggest that the two proteins do not interact in the solution phase [14].
WebFeb 23, 2024 · We identify cytohesin 1 (CYTH1) as a novel regulator of human HSPC adhesion in vitro and a critical mediator of homing and engraftment in vivo. ... Initially, …
WebTo analyze the interaction of Fyn with cytohesin-1, we transfected human embryonic kidney (HEK) 293T cells with plasmid encoding wild-type cytohesin-1, which we then purified (fig. S5A) and showed to be free of either Arf1 or Arf6 (fig. S5B). ... The abundance of the Y382F mutant cytohesin-1 protein was greater in TG#5 Schwann cells than in TG ... crystal vision cvt9604e-3010w user manualWebThis workflow (SUMO) activating protein 1 (SUMO E1) [51,52]. We docked a small was employed to identify compounds with potent anti-tubercular molecule library to the ATP binding site in SUMO E1 using a activities [71]. In another excellent LBSB-HLVS study, Liu et al. [72] two-step molecular docking strategy. crystal vision cvt804c-30wbWebGoodrum FD, et al. Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells. J. Virol. 70: 6323-6335, 1996. PubMed: 8709260 . Kolanus W, et al. alphaLbeta2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1 a cytoplasmic regulatory molecule. crystal vision cvt9608e-3010w manualWebThe precise role of periostin, an extra-cellular matrix protein, in inflammatory bowel disease (IBD) is unclear. Here, we investigated periostin in paediatric IBD including its relationship with disease activity, clinical outcomes, genomic variation crystal vision default passwordWebMar 4, 1997 · Cytohesin-1, a protein abundant in cells of the immune system, has been proposed to be a human homolog of the Saccharomyces cerevisiae Sec7 gene product, which is crucial in protein transport. More recently, the same protein has been reported to be a regulatory factor for the αLβ2 integrin in lymphocytes. crystal vision eye centerWebCytohesin 1 Interacting Protein Human Recombinant PRO-2172. 5µg ($60) 20µg ($145) ... (PSCD1), Cytohesin-1 is a member of the cytohesin family. CYTH Structure Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain ... crystal vision filmsWebSymbol Description Category UniProt ID GIFtS GC id Score; 276: piR-41306-047: RNA Gene: 2: GC11P082785: 0.92: 277: CDC73: Cell Division Cycle 73: Protein Coding ... crystal vision fleetwood mac